Botanic Sanctuary Antwerp is the grandest stay in the city. The five-star hotel, a member of The Leading Hotels of the World, occupies a cluster of historic buildings around green courtyards on the Leopoldstraat, right beside the small Botanical Garden, and feels like a walled retreat in the middle of town. It has 108 rooms and suites, four restaurants and a bar on site, with the fine-dining Hertog Jan at Botanic and Bar Bulot by Hertog Jan just steps away, and a wellness floor with the Botanic Health Spa, an indoor pool, a health club and classes. The Meir shopping street and the diamond district are about ten minutes on foot, the KMSKA and the old town are an easy walk or tram ride, and Antwerp Central Station is around a quarter of an hour on foot. It is the place for a special occasion.
Location and getting around: the hotel sits on the Leopoldstraat, between the Meir and the Zuid district. The Botanical Garden is next door, the Meir and the diamond district are about nine minutes on foot, the Rubens Experience is close by and the cathedral is a pleasant walk through the shopping streets. Antwerp Central is around seventeen minutes on foot, so take a taxi with luggage.
The rooms: rooms and suites are spread across the historic buildings, so they vary in size and outlook. Ask for a room facing the inner gardens if you want quiet, and choose a suite if you want more space for a longer stay.
Who it suits: couples on a romantic break, food lovers who want to dine at Hertog Jan, and anyone who values a spa and pool on site. Business travellers like the calm. Families can book larger rooms, but the mood is grown-up.
Good to know: breakfast is a buffet for a surcharge and gets warm reviews. Valet parking is available at a daily fee. Expedia notes that the indoor pool is unavailable from 1 to 19 November 2026, so check before booking a spa break in that period. An airport shuttle can be arranged for a fee.
Why stay here
- ✓Botanic Health Spa
- ✓Indoor pool
- ✓Health club and fitness classes
- ✓Four restaurants and a bar
- ✓Next to the Botanical Garden
- ✓Valet parking
- ✓Airport shuttle on request
- ✓Buffet breakfast
Good questions
Where is Botanic Sanctuary Antwerp?+
It is at Leopoldstraat 26A, next to the Botanical Garden and about nine minutes on foot from the Meir. Antwerp Central Station is around seventeen minutes away on foot.
Does Botanic Sanctuary have a pool and spa?+
Yes, it has the Botanic Health Spa, an indoor pool and a health club. Expedia lists the pool as unavailable from 1 to 19 November 2026.
Is breakfast included?+
Breakfast is a buffet served for a surcharge unless your rate includes it. Guests often praise it in reviews.








