Choosing a base is the biggest decision on a Sicily trip, because the sights are spread far apart. The good news is that the three main bases each have a distinct personality, and each suits a different traveller.
Palermo: the historic centre
If you want Arab-Norman monuments, markets, churches and a big-city feel, stay in or near the old town. The Massimo Plaza Hotel, on Via Maqueda opposite the Teatro Massimo, is a practical mid-range base: the Quattro Canti, the Cathedral, the Ballarò market and the Norman Palace are a walk away, and evening opera is just across the road. The trade-off is city noise, so ask for a higher floor. This area suits first-timers, culture lovers and anyone who wants to travel without a car.
Palermo: the seafront villa
For a romantic, resort-like stay with a city break attached, Villa Igiea in the Acquasanta district is a different experience. It is a Rocco Forte Art Nouveau palace with terraced gardens and sea views, about ten minutes by taxi from the old centre. It is for couples and special occasions, and for travellers who want to sightsee by day and retreat to a calm place in the evening. Rates are at the top of the market.
Taormina: the resort town
Taormina sits on a hillside above the Ionian Sea, with the Greek Theatre, a pedestrian Corso Umberto and views of Etna. It is beautiful and busy, with prices to match, and it is smaller than people expect, so two or three nights are enough. Hotel Villa Ducale, uphill from the centre, offers garden terraces and bay views in a quiet, family-run setting, and suits couples who like calm. Hotel Isabella, in the old town, is a budget-friendly option where the location does the work: you walk to the theatre, the Corso and the restaurants. Remember that the old town is pedestrian, so check luggage and taxi arrangements.
Catania: the practical hub
Catania is a gritty, lively baroque city with the best food scene in the east, and it is the easiest base for Mount Etna, Syracuse and the airport. NH Catania Centro, near Via Etnea and a few minutes from the old town, is a modern, reliable choice with a rooftop terrace and a free gym. It suits families, business travellers and anyone who wants convenience and a strong food scene. Catania is less polished than Taormina, which is part of its charm.
How to choose
For a first visit of a week, split your nights: three in Palermo, three in Taormina or Catania. If you have only a few days, pick one side. If you love art and history, favour Palermo. If you want views and relaxation, choose Taormina. If you want food, volcanoes and easy day trips, base in Catania.
Practical notes
Book early for spring, summer and festival weekends, since the best central rooms sell out. Ask about parking and luggage access in pedestrian zones, and confirm breakfast and cancellation terms. Whichever you choose, you will be well placed for the Twickly attractions: the Norman Palace and Monreale from Palermo, the Greek Theatre and Etna from Taormina and Catania, and the street food tours in both cities.

